| Long name: |
FITC Conjugated, Tie2 (Tyr992) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tie2 Tyr992 |
| Specificity: |
This is a highly specific antibody against Tie2 Tyr992 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr992 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tie2 around the phosphorylation site of Tyr992 |
| Gene ID number: |
7010 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202b, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specic receptor tyrosine kinase 2, Hyk, Soluble TIE2 variant 1, Soluble TIE2 variant 2, TEK tyrosine kinase endothelial, TIE 2, TIE2_HUMAN, Tek, Tie2, Tunica interna endothelial cell kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains 2, Tyrosine protein kinase receptor TEK, Tyrosine protein kinase receptor TIE 2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, Tyrosine-protein kinase receptor TIE-2, VMCM, VMCM 1, VMCM1, Venous malformations multiple cutaneous and mucosal, endothelial, hTIE 2, hTIE2, p140 TEK, tek tyrosine kinase, tek tyrosine kinase, Tie-2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tie2 (Tyr992) Conjugated |
| Short name: |
FITC Conjugated, Tie2 (Tyr992) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Tie2 (Tyr992) (Antibody to) |
| Alternative technique: |
antibodies |