| Long name: |
FITC Conjugated, Stat2 (Tyr690) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Stat2 Tyr690 |
| Specificity: |
This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat, This is a highly specific antibody against Stat2 Tyr690 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr690 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
670-720/851 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690 |
| Gene ID number: |
6773 |
| Swiss Prot: |
P52630 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Following type I IFN binding to cell surface receptors, ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, Jak kinases (TYK2 and JAK1) are activated, The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, leading to tyrosine phosphorylation of STAT1 and STAT2, that enters the nucleus, which drive the cell in an antiviral state, Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ISGF-3, STAT113, STAT2, Signal transducer and activator of transcription 2, P113 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Stat2 (Tyr690) Conjugated |
| Short name: |
FITC Conjugated, Stat2 (Tyr690) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
113kDa (Tyr690) (Antibody to), fluorecein coupled, signal transducer and activator on transcription 2 |
| Alternative technique: |
antibodies |