| Long name: |
Cy7 Conjugated, SGK1 (Ser422) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SGK1 Ser422 |
| Specificity: |
This is a highly specific antibody against SGK1 Ser422 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser422 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
400-431/431 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser422 |
| Gene ID number: |
6446 |
| Swiss Prot: |
O00141 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy, Jan 2009], Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene, This kinase activates certain potassium, [provided by RefSeq, and chloride channels, and renal sodium excretion, neuronal excitability, sodium, suggesting an involvement in the regulation of processes such as cell survival, This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
SGK1 (Ser422) Conjugated |
| Short name: |
Conjugated, SGK1 (Ser422) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, serum/glucocorticoid regulated kinase 1 (Ser422) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
SGK, SGK1 and IDBG-633483 and ENSBTAG00000004269 and 515854, SGK1 and IDBG-96775 and ENSG00000118515 and 6446, Sgk1 and IDBG-137283 and ENSMUSG00000019970 and 20393, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007616 and long-term memory and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005246 : calcium channel regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005246 : calcium channel regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015459 : potassium channel regulator activity, this GO :0016772 : transferase activity, this GO :0017080 : sodium channel regulator activity, this GO :0017081 : chloride channel regulator activity, this GO :0035091 : phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080 : sodium channel regulator activity and also this GO :0017081 : chloride channel regulator activity and also this GO :0035091 : phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0032411 and positive regulation of transporter activity and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060453 and regulation of gastric acid secretion and biological process this GO :0070294 and renal sodium ion absorption and biological process, serum/glucocorticoid regulated kinase 1 |
| Identity: |
10810 |
| Gene: |
SGK1 |
More about : SGK1 |
| Long gene name: |
serum/glucocorticoid regulated kinase 1 |
| Synonyms gene: |
SGK |
| Synonyms gene name: |
serum/glucocorticoid regulated kinase |
| Locus: |
6q23, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AJ000512 |
| Entrez gene record: |
6446 |
| Pubmed identfication: |
9114008 9722955 |
| Havana BLAST/BLAT: |
OTTHUMG00000015613 |