| Long name: |
Cy3 Conjugated, SGK1 (Ser422) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SGK1 Ser422 |
| Specificity: |
This is a highly specific antibody against SGK1 Ser422 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser422 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
400-431/431 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser422 |
| Gene ID number: |
6446 |
| Swiss Prot: |
O00141 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy, Jan 2009], Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene, This kinase activates certain potassium, [provided by RefSeq, and chloride channels, and renal sodium excretion, neuronal excitability, sodium, suggesting an involvement in the regulation of processes such as cell survival, This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the SGK1 (Ser422) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SGK1 (Ser422) Conjugated |
| Short name: |
Conjugated, SGK1 (Ser422) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, serum/glucocorticoid regulated kinase 1 (Ser422) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
SGK, SGK1 and IDBG-633483 and ENSBTAG00000004269 and 515854, SGK1 and IDBG-96775 and ENSG00000118515 and 6446, Sgk1 and IDBG-137283 and ENSMUSG00000019970 and 20393, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007616 and long-term memory and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005246 : calcium channel regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005246 : calcium channel regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015459 : potassium channel regulator activity, this GO :0016772 : transferase activity, this GO :0017080 : sodium channel regulator activity, this GO :0017081 : chloride channel regulator activity, this GO :0035091 : phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080 : sodium channel regulator activity and also this GO :0017081 : chloride channel regulator activity and also this GO :0035091 : phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0032411 and positive regulation of transporter activity and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060453 and regulation of gastric acid secretion and biological process this GO :0070294 and renal sodium ion absorption and biological process, serum/glucocorticoid regulated kinase 1 |
| Identity: |
10810 |
| Gene: |
SGK1 |
More about : SGK1 |
| Long gene name: |
serum/glucocorticoid regulated kinase 1 |
| Synonyms gene: |
SGK |
| Synonyms gene name: |
serum/glucocorticoid regulated kinase |
| Locus: |
6q23, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AJ000512 |
| Entrez gene record: |
6446 |
| Pubmed identfication: |
9114008 9722955 |
| Havana BLAST/BLAT: |
OTTHUMG00000015613 |