| Long name: |
FITC Conjugated, Ret (Tyr905) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ret Tyr905 |
| Specificity: |
This is a highly specific antibody against Ret Tyr905 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr905 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Ret around the phosphorylation site of Tyr905 |
| Gene ID number: |
5979 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Active in the absence of ligand, Acts as a dependence receptor, ITGB1 and ITGB3)-dependent manner, Involved in the development of the neural crest, Mediator of several diseases such as neuroendocrine cancers, Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e, Phosphorylates PTK2/FAK1, Regulates both cell death/survival balance and positional information, Regulates nociceptor survival and size, Required for the molecular mechanisms orchestration during intestine organogenesis, Triggers the differentiation of rapidly adapting (RA) mechanoreceptors, a major component of the gut-associated lymphoid tissue, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands, and promotes the formation of Peyer's patch-like structures, but triggers apoptosis in absence of GDNF, cell migration, in the presence of the ligand GDNF in somatotrophs (within pituitary), involved in the development of enteric nervous system and renal organogenesis during embryonic life, neuronal navigation, promotes survival and down regulates growth hormone (GH) production, these diseases are characterized by aberrant integrins-regulated cell migration, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage, Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, g |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CDHF 12, CDHF12, CDHR16, Cadherin family member 12, Cadherin related family member 16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, PTC, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, RET, RET ELE1, RET transforming sequence, RET51, RET9, RET_HUMAN, Ret Proto oncogene, tyrosine-protein kinase receptor ret, C ret |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ret (Tyr905) Conjugated |
| Short name: |
FITC Conjugated, Ret (Tyr905) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ret proto-oncogene (Tyr905) (Antibody to) |
| Alternative technique: |
antibodies |