| Long name: |
ALEXA FLUOR 350 Conjugated, c-Raf (Ser259) Polyclonal Antibody |
| Also known as: |
Anti-c-Raf Ser259 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
c-Raf Ser259 |
| Specificity: |
This is a highly specific antibody against c-Raf Ser259 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser259 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser259 |
| Gene ID Number: |
5894 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It is part of the Ras dependent signaling pathway from receptors to the nucleus, Raf1 is involved in the transduction of mitogenic signals from the cell membrane to the nucleus, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated, bRaf, cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, phosphorylates MEK which in turn phosphorylates ERK, The Raf family of serine/threonine specific kinases is comprised of three members (aRaf |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
6430402F14Rik, AA990557, BB129353, C-RAF, Craf 1 transforming gene, Craf1, Craf1 transforming gene, D830050J10Rik, EC 2, MGC102375, Murine sarcoma 3611 oncogene 1, RAF, RAF1, Raf 1, Raf proto oncogene serine/threonine protein kinase, Raf-1, Raf1Ser259, c Raf, c-Raf, c-Raf, cRaf, murine leukemia viral v-raf-1 oncogene homolog 1 3611-MSV, proto-oncogene c-RAF, v-Raf, v-raf-1 murine leukemia viral oncogene homolog 1, vraf1 murine leukemia viral oncogene homolog 1, 1, 7, 11, RAF1phospho S259 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
c-Raf (Ser259) |
| Short name: |
c-Raf (Ser259) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, c-Raf (Ser259) (Antibody to) |
| Alternative technique: |
antibodies |