| Long name: |
Biotin Conjugated, PSD93 (Tyr340) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PSD93 Tyr340 |
| Specificity: |
This is a highly specific antibody against PSD93 Tyr340 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr340 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PSD93 around the phosphorylation site of Tyr340 |
| Gene ID number: |
1740 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif, Neuronal nitric oxide synthase (nNOS), Other neuronal proteins that share this motif (beta 1 adrenergic receptor, There are two principal modes of interaction between PSD 93 and other proteins, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane, some serotonin receptors, some sodium channel subunits, which lacks the T/SXV motif but which has its own PDZ domain, PSD 93 is believed to participate in the clustering of certain proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PSD-93 PSD93 chapsyn-110 PPP1R58 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PSD93 (Tyr340) Conjugated |
| Short name: |
Conjugated, PSD93 (Tyr340) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PSD93 (Tyr340) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2901 |
| Gene: |
DLG2 |
More about : DLG2 |
| Long gene name: |
discs large MAGUK scaffold protein 2 |
| Synonyms gene name: |
chapsyn-110 (Drosophila) discs, discs, large homolog 2, large homolog 2 (Drosophila) discs large homolog 2 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 58 |
| Locus: |
11q14, 1 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
U32376 |
| Entrez gene record: |
1740 |
| Pubmed identfication: |
8755482 9806853 |
| RefSeq identity: |
NM_001364 |
| Classification: |
Protein phosphatase 1 regulatory subunits Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134309 |