| Long name: |
ALEXA FLUOR 488 Conjugated, IKK alpha/IKK beta (S180/S181) Antibody |
| Also known as: |
Anti-IKK alpha/IKK beta Ser180/Ser181 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IKK alpha/IKK beta Ser180/Ser181 |
| Specificity: |
This is a highly specific antibody against IKK alpha/IKK beta Ser180/Ser181 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser180/Ser181 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human IKK alpha/IKK beta around the phosphorylation site of Ser180/Ser181 |
| Gene ID Number: |
1147 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
IKK alpha and IKK beta interact with each other and both are essential for NFkB activation, IKK alpha specifically phosphorylates IkBa, IKK is a serine protein kinase, IKKa is expressed in variety of human tissues, NFkB is associated with IkB proteins in the cell cytoplasm, NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta), which inhibit NFkB activity, Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CHUK1, Conserved Helix Loop Helix Ubiquitous Kinase, Conserved helix loop ubiquitous kinase, I Kappa B Kinase 1, IKBKA, IKK 1, IKK A, IKK a kinase, IKK alpha, IKK1, IKKA, IKKA_HUMAN, IKKalpha, IkB kinase alpha subunit, IkappaB kinase, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, NFKBIKA, Nuclear Factor Kappa B Inhibitor Kinase Alpha, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear factor NFkappaB inhibitor kinase alpha, TCF16, I Kappa B Kinase Alpha |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IKK alpha/IKK beta (S180/S181) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
IKK alpha/IKK beta (S180/S181) |
| Short name: |
IKK alpha/IKK beta (S180/S181) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, IKK a/IKK b (S180/S181) (Antibody to) |
| Alternative technique: |
antibodies |