| Long name: |
HER4 (Tyr1284) Primary Polyclonal Antibody |
| Also known as: |
HER4 (Tyr1284) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HER4 Tyr1284 |
| Specificity: |
This is a highly specific antibody against HER4 Tyr1284 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr1284 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1284 |
| Gene ID number: |
2066 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternatively spliced variants which encode different protein isoforms have been described, It encodes a single-pass type I membrane protein with multiple cysteine rich domains, Jul 2008], Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment, Mutations in this gene have been associated with cancer, The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation, [provided by RefSeq, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif, a transmembrane domain, a tyrosine kinase domain, however, not all variants have been fully characterized, This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Avian erythroblastic leukemia viral oncogene homolog 4, Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4, ErbB4, HER 4, HER4, MGC138404, P180erbB4, Receptor protein tyrosine kinase erbB 4 precursor, Receptor tyrosine protein kinase erbB 4, VERBB2, Verba avian erythroblastic leukemia viral oncogene homolog like 4, Verba erythroblastic leukemia viral oncogene homolog 4, p-ErbB 4 phospho Y1284, v erb a avian erythroblastic leukemia viral oncogene homolog like 4, v erb a erythroblastic leukemia viral oncogene homolog 4, ErbB 4 phospho Y1284, Tyrosine kinase type cell surface receptor HER4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HER4 (Tyr1284) |
| Short name: |
HER4 (Tyr1284) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HER4 (Tyr1284) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3432 |
| Gene: |
ERBB4 |
More about : ERBB4 |
| Long gene name: |
erb-b2 receptor tyrosine kinase 4 |
| Synonyms gene name: |
v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 |
| Synonyms: |
ALS19 HER4 |
| Synonyms name: |
human epidermal growth factor receptor 4 |
| Locus: |
2q34 |
| Discovery year: |
1995-09-07 |
| GenBank acession: |
L07868 |
| Entrez gene record: |
2066 |
| Pubmed identfication: |
7700649 17018285 |
| RefSeq identity: |
NM_001042599 |
| Classification: |
Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000133012 |