| Long name: |
ALEXA FLUOR 555 Conjugated, GAB2 (Tyr452) Polyclonal Antibody |
| Also known as: |
Anti-GAB2 Tyr452 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GAB2 Tyr452 |
| Specificity: |
This is a highly specific antibody against GAB2 Tyr452 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr452 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
430-470/676 |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Tyr452 |
| Gene ID Number: |
9846 |
| Swiss Prot: |
Q9UQC2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also involved in the regulation of cell proliferation and hematopoiesis, In allergic response, Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling, antigen, cell matrix and growth factor receptors to regulate multiple signaling pathways, hormone, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation, Adapter protein which acts downstream of several membrane receptors including cytokine |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
KIAA0571 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
GAB2 (Tyr452) |
| Short name: |
GAB2 (Tyr452) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, GRB2-associated binding protein 2 (Tyr452) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0005547 : phosphatidylinositol-3, this GO :0043325 : phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325 : phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2 |
| Identity: |
14458 |
| Gene: |
GAB2 |
More about : GAB2 |
| Long gene name: |
GRB2 associated binding protein 2 |
| Synonyms name: |
Grb2-associated binder 2 |
| Locus: |
11q14, 1 |
| Discovery year: |
2001-01-24 |
| GenBank acession: |
AB011143 |
| Entrez gene record: |
9846 |
| Pubmed identfication: |
10391903 10068651 |
| RefSeq identity: |
NM_080491 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166673 |