| Long name: |
c-Fos (Thr325) Primary Polyclonal Antibody |
| Also known as: |
c-Fos (Thr325) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
c-Fos Thr325 |
| Specificity: |
This phosphorylation site is homologous to Thr325 in Mouse and Rat, This is a highly specific antibody against c-Fos Thr325 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr325 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-350/380 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Thr325 |
| Gene ID number: |
2353 |
| Swiss Prot: |
P01100 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites, Has a critical function in regulating the development of cells destined to form and maintain the skeleton, In growing cells, In the heterodimer, It is thought to have an important role in signal transduction, On TGF-beta activation, This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum, activates phospholipid synthesis, cell proliferation and differentiation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling, possibly by activating CDS1 and PI4K2A, Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AP-1, C-FOS, Cellular oncogene fos, FOS, G0/G1 switch regulatory protein 7, G0S7, Proto-oncogene c-Fos, p55 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Fos (Thr325) |
| Short name: |
c-Fos (Thr325) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
c-FBJ murine osteosarcoma viral oncogene homolog (Thr325) (Antibody to) |
| Alternative technique: |
antibodies |