| Long name: |
ALEXA FLUOR 647 Conjugated, Caspase-9 (Tyr153) Polyclonal Antibody |
| Also known as: |
Anti-Caspase-9 Tyr153 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Caspase-9 Tyr153 |
| Specificity: |
This is a highly specific antibody against Caspase-9 Tyr153 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr153 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 |
| Gene ID Number: |
842 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BclXL, Caspase 3, Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin, Caspase 9 is inhibited by the dominant negative isoform, Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6, ProCaspase 9 has been reported to be approximately 47 kD, This caspase becomes activated when recruited to Apaf1/cytochrome c complex, This caspase is active as a heterotetramer and has been reported to have two isoforms, This caspase is present in the cytosol and, XIAP, and Livin, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain, and following cleavage by Apaf1, apoptotic protease Mch6, cIAP1, cIAP2, granzyme B, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits, translocates to the mitochondria, upon activation, Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch 6, Apoptotic protease activating factor 3, CASP 9, CASP9, CASP9_HUMAN, Caspase 9 Dominant Negative, Caspase 9 precursor, Caspase 9c, Caspase9, EC 3, ICE LAP6, ICE like apoptotic protease 6, MCH6 antibody RNCASP9, 4, 22, APAF 3 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Caspase-9 (Tyr153) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Caspase-9 (Tyr153) |
| Short name: |
Caspase-9 (Tyr153) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, caspase-9 (Tyr153) (Antibody to) |
| Alternative technique: |
antibodies |