| Long name: |
ALEXA FLUOR 594 Conjugated, ATXN1 (Ser775) Polyclonal Antibody |
| Also known as: |
Anti-ATXN1 Ser775 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATXN1 Ser775 |
| Specificity: |
This is a highly specific antibody against ATXN1 Ser775 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser775 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775 |
| Gene ID Number: |
6310 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D6S504E ATX1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
ATXN1 (Ser775) |
| Short name: |
ATXN1 (Ser775) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, ATXN1 (Ser775) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10548 |
| Gene: |
ATXN1 |
More about : ATXN1 |
| Long gene name: |
ataxin 1 |
| Synonyms gene: |
SCA1 |
| Synonyms gene name: |
ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1 |
| Locus: |
6p22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X79204 |
| Entrez gene record: |
6310 |
| Pubmed identfication: |
1582256 |
| RefSeq identity: |
NM_000332 |
| Classification: |
Ataxins |
| Havana BLAST/BLAT: |
OTTHUMG00000014303 |
| Locus Specific Databases: |
LRG_863 |