P105 RB Antibody, Cy5 Conjugated

Catalog number:	bs-2777R-Cy5 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	P105 RB Antibody, Cy5 Conjugated
Quantity:	0.1ml
Related search:	antibody gene conjugated complex histone nfkb year

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Long name:	Cy5 Conjugated, P105 RB Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	P105 RB
Specificity:	This is a highly specific antibody against P105 RB
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	68-116/928
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic peptide derived from human Rb/P105 RB
Gene ID number:	5925
Swiss Prot:	P06400
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Acts as a transcription repressor of E2F1 target genes, Controls histone H4 'Lys-2' trimethylation, Directly involved in heterochromatin formation by maintaining overall chromatin structure and, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity, In case of viral infections, In resting neurons, Inhibits the intrinsic kinase activity of TAF1, Mediates transcriptional repression by SMARCA4/BRG1 by recruiting a histone deacetylase (HDAC) complex to the c-FOS promoter, Promotes G-G1 transition when phosphorylated by CDK3/cyclin-C, RB1 is dephosphorylated by calcineurin, Recruits and targets histone methyltransferases SUV39H1, SUV42H1 and SUV42H2, The underphosphorylated, Upon calcium influx, active form of RB1 interacts with E2F1 and represses its transcription activity, in particular, interactions with SV4 large T antigen, leading to cell cycle arrest, leading to epigenetic transcriptional repression, that of constitutive heterochromatin by stabilizing histone methylation, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex, which leads to release of the repressor complex (By similarity), Key regulator of entry into cell division that acts as a tumor suppressor
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	LYT-10 p52 p105 NF-kB2 p49/p100
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	P105 RB Conjugated
Short name:	Conjugated, P105 RB Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, P105 RB (Antibody to)
Alternative technique:	antibodies
Identity:	7795
Gene:	NFKB2 | More about : NFKB2
Long gene name:	nuclear factor kappa B subunit 2
Synonyms gene name:	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus:	10q24, 32
Discovery year:	1991-11-14
GenBank acession:	X61498
Entrez gene record:	4791
Pubmed identfication:	1876189
Classification:	Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT:	OTTHUMG00000018962

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