| Long name: |
FITC Conjugated, Aurora A+B+C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Aurora A+B+C |
| Specificity: |
This is a highly specific antibody against Aurora A+B+C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Aurora A/B/C |
| Gene ID number: |
6790 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Aurora A is viewed as a potential target for anticancer drug treatment, Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis, Aurora-C expression is maximum at M phase, Elevated expression levels are seen only in a subset of cancer cells such as HepG2, Expression is limited to testis in normal cells, HuH7 and HeLa cells, It localizes to the inner centromere region from prophase to anaphase, The Aurora kinases, This protein is localized to centrosome from anaphase to cytokinesis, and may regulate several stages of mitosis such as centrosome separation, associate with microtubules during chromosome movement and segregation, behaves as a chromosomal passenger protein, chromosome segregation and cytokinesis, in relation to the function of the centrosome/spindle pole region during chromosome segregation, members of the Ser/Thr protein kinase family, ovarian and colorectal, Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
AIE2, AIK2, AIK3, AIM1, ARK1, ARK2, AURA, AURKA, AURKA_HUMAN, AURKB, AURKC, AURKC, AURORA2, AYK1, AurB, AurC, Aurora 1, Aurora 2, Aurora A, Aurora C, Aurora Family Kinase 1, Aurora Related Kinase 1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora related kinase 2, Aurora-B, Aurora/IPL1 Like Kinase, Aurora/IPL1 Related Kinase 1, Aurora/IPL1 related kinase 2, Aurora/Ipl1 related kinase 3, Aurora/Ipl1/Eg2 protein 2, BRAK, BTAK, Breast Tumor Amplied Kinase, EC 2, IAK, IPL-1, IPL1, IPL1 Aurora Related Kinase 1, IPL1 Related Kinase, MGC34538, STK1, STK12, STK13, STK5, Serine threonine protein kinase 13, Serine/theronine kinase 12, Serine/threonine protein kinase 12, aurora kinase A, hARK1, 1, 7, 11, AIK |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Aurora A+B+C Conjugated |
| Short name: |
FITC Conjugated, Aurora A+B+C Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Aurora A+B+C (Antibody to) |
| Alternative technique: |
antibodies |