| Long name: |
ALEXA FLUOR 555 Conjugated, FANCD2 Polyclonal Antibody |
| Also known as: |
Anti-FANCD2 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FANCD2 |
| Specificity: |
This is a highly specific antibody against FANCD2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FANCD2 |
| Gene ID Number: |
2177 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation, and cellular hypersensitivity to mitomycin C (MMC), progressive bone marrow failure, targeting nuclear foci containing the BRCA 1 protein, DNA damage activates the monoubiquitination of FANC D2, Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
FAD FA-D2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
FANCD2 |
| Short name: |
FANCD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, complementation family D2 (Antibody to), Fanconi anemia |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA polymerase binding, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, complementation group D2, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006281 and DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007129 and synapsis and biological process this GO :0007276 and gamete generation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070182 and DNA polymerase binding and molecular function, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0070182 : DNA polymerase binding, this GO :0005515 : protein binding, this GO :0070182 : DNA polymerase binding, Fanconi anemia |
| Identity: |
3585 |
| Gene: |
FANCD2 |
More about : FANCD2 |
| Long gene name: |
Fanconi anemia complementation group D2 |
| Synonyms gene: |
FACD FANCD |
| Locus: |
3p25, 3 |
| Discovery year: |
1996-01-04 |
| GenBank acession: |
AF340183 |
| Entrez gene record: |
2177 |
| Pubmed identfication: |
7581463 11239453 18475298 |
| Classification: |
Fanconi anemia complementation groups |
| Havana BLAST/BLAT: |
OTTHUMG00000128670 |
| Locus Specific Databases: |
Fanconi Anaemia Mutation Database Fanconi anemia database LRG_306 |