| Long name: |
DKK3 Primary Polyclonal Antibody |
| Also known as: |
DKK3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DKK3 |
| Specificity: |
This is a highly specific antibody against DKK3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
50-85/350 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DKK3 |
| Gene ID number: |
27122 |
| Swiss Prot: |
Q9UBP4 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DKKs play an important role in vertebrate development, Dkks are implicated in bone formation and bone disease, In the adult, cancer and Alzheimer disease (By similarity), limb development, somitogenesis and eye formation, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DKK3, Dickkopf-3, Dickkopf-related protein 3, Dkk-3, REIC, UNQ258/PRO295, hDkk-3, RIG |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DKK3 |
| Short name: |
DKK3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DKK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2893 |
| Gene: |
DKK3 |
More about : DKK3 |
| Long gene name: |
dickkopf WNT signaling pathway inhibitor 3 |
| Synonyms gene name: |
dickkopf (Xenopus laevis) homolog 3 dickkopf 3 homolog (Xenopus laevis) |
| Synonyms: |
REIC RIG |
| Synonyms name: |
regulated in glioma |
| Locus: |
11p15, 3 |
| Discovery year: |
2000-09-01 |
| GenBank acession: |
AF177396 |
| Entrez gene record: |
27122 |
| Pubmed identfication: |
10570958 |
| RefSeq identity: |
NM_013253 |
| Havana BLAST/BLAT: |
OTTHUMG00000165709 |