| Long name: |
Langerin/CD207 Primary Polyclonal Antibody |
| Also known as: |
Langerin/CD207 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Langerin/CD207 |
| Specificity: |
This is a highly specific antibody against Langerin/CD207 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
213-223/328 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD207 |
| Gene ID number: |
50489 |
| Swiss Prot: |
Q9UJ71 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation, Binds to sulfated as well as mannosylated glycans, Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells, Induces the formation of Birbeck granules (BGs), Major receptor on primary Langerhans cells for Candida species, Protects against human immunodeficiency virus-1 (HIV-1) infection, Saccharomyces species, and Malassezia furfur, is a potent regulator of membrane superimposition and zippering, keratan sulfate (KS) and beta-glucans, Calcium-dependent lectin displaying mannose-binding specificity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-type lectin domain family 4 member K, CD207, Langerin, CLEC4K |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Langerin/CD207 |
| Short name: |
Langerin/CD207 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
langerin (Antibody to), Langerin/CD207 molecule |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD207 and IDBG-55659 and ENSG00000116031 and 50489, CD207 and IDBG-631820 and ENSBTAG00000004562 and 511000, Cd207 and IDBG-161509 and ENSMUSG00000034783 and 246278, Plasma membranes, TAP-dependent and biological process this GO :0005537 and mannose binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0030669 and clathrin-coated endocytic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0051607 and defense response to virus and biological process, carbohydrate binding, langerin, this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005537 : mannose binding, this GO :0005537 : mannose binding and also this GO :0030246 : carbohydrate binding, this GO :0030246 : carbohydrate binding, CD207 molecule |
| Identity: |
17935 |
| Gene: |
CD207 |
More about : CD207 |
| Long gene name: |
CD207 molecule |
| Synonyms gene name: |
CD207 antigen, langerin , langerin CD207 molecule |
| Synonyms: |
Langerin CLEC4K |
| Locus: |
2p13, 3 |
| Discovery year: |
2003-10-02 |
| GenBank acession: |
AJ242859 |
| Entrez gene record: |
50489 |
| Pubmed identfication: |
10661407 9847074 |
| RefSeq identity: |
NM_015717 |
| Classification: |
CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000153176 |