| Long name: |
Cy5, 5 Conjugated, CCL19/MIP-3 beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCL19/MIP-3 beta |
| Specificity: |
This is a highly specific antibody against CCL19/MIP-3 beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
60-100/108 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse CCL19 |
| Gene ID number: |
24047 |
| Swiss Prot: |
O70460 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4, Binds to chemokine receptor CCR7, May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues, Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
ELC MIP-3b exodus-3 CKb11 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
CCL19/MIP-3 beta Conjugated |
| Short name: |
Conjugated, CCL19/MIP-3 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, chemokine (C-C motif) ligand 19/MIP-3 b (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCL19 and IDBG-61011 and ENSG00000172724 and 6363, CCL19 and IDBG-635974 and ENSBTAG00000012684 and 509167, CCR chemokine receptor binding, CKb11 and ELC and MIP-3b and MIP3B and SCYA19, Extracellular, this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002408 and myeloid dendritic cell chemotaxis and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007154 and cell communication and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008009 and chemokine activity and molecular function this GO :0009615 and response to virus and biological process this GO :0010560 and positive regulation of glycoprotein biosynthetic process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0031732 and CCR7 chemokine receptor binding and molecular function this GO :0031735 and CCR10 chemokine receptor binding and molecular function this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042379 and chemokine receptor binding and molecular function this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045627 and positive regulation of T-helper 1 cell differentiation and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048020 and CCR chemokine receptor binding and molecular function this GO :0048260 and positive regulation of receptor-mediated endocytosis and biological process this GO :0048469 and cell maturation and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060491 and regulation of cell projection assembly and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071731 and response to nitric oxide and biological process this GO :0072610 and interleukin-12 secretion and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097029 and mature dendritic cell differentiation and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000549 and positive regulation of dendritic cell dendrite assembly and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0031732 : CCR7 chemokine receptor binding and also this GO :0031735 : CCR10 chemokine receptor binding and also this GO :0042379 : chemokine receptor binding and also this GO :0048020 : CCR chemokine receptor binding, this GO :0031732 : CCR7 chemokine receptor binding, this GO :0031735 : CCR10 chemokine receptor binding, this GO :0042379 : chemokine receptor binding, this GO :0048020 : CCR chemokine receptor binding, chemokine (C-C motif) ligand 19 |
| Identity: |
10617 |
| Gene: |
CCL19 |
More about : CCL19 |
| Long gene name: |
C-C motif chemokine ligand 19 |
| Synonyms gene: |
SCYA19 |
| Synonyms gene name: |
member 19 chemokine (C-C motif) ligand 19 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms name: |
CC chemokine ligand 19 macrophage inflammatory protein 3-beta beta chemokine exodus-3 CK beta-11 EBI1-ligand chemokine |
| Locus: |
9p13, 3 |
| Discovery year: |
1997-02-19 |
| GenBank acession: |
AB000887 |
| Entrez gene record: |
6363 |
| Pubmed identfication: |
9153236 |
| RefSeq identity: |
NM_006274 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000019833 |