| Long name: |
Dysferlin Primary Polyclonal Antibody |
| Also known as: |
Dysferlin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Dysferlin |
| Specificity: |
This is a highly specific antibody against Dysferlin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dysferlin |
| Gene ID number: |
8291 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternative splicing results in multiple transcript variants, Aug 2008], In addition, It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy, [provided by RefSeq, a skeletal muscle membrane protein which is important in the formation of caveolae, suggesting that it may be involved in membrane regeneration and repair, the protein encoded by this gene binds caveolin-3, The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DYSF, DYSF_HUMAN, Dysferlin Dystrophy associated fer 1 like protein Fer 1 like protein 1, Dysferlin limb girdle muscular dystrophy 2B, Dysferlin limb girdle muscular dystrophy 2B autosomal recessive, Dystrophy associated fer 1 like 1, Dystrophy associated fer 1 like protein, Dystrophy associated fer1 like 1, Dystrophy associated fer1 like protein, FER1L1, FLJ00175, FLJ90168, Fer 1 like protein 1, Fer1 like protein 1, LGMD 2B, LGMD2B, Limb girdle muscular dystrophy 2B, Limb girdle muscular dystrophy 2B autosomal recessive , MM, Miyoshi myopathy, DMAT |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Dysferlin |
| Short name: |
Dysferlin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Dysferlin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3097 |
| Gene: |
DYSF |
More about : DYSF |
| Long gene name: |
dysferlin |
| Synonyms gene: |
LGMD2B |
| Synonyms gene name: |
limb girdle muscular dystrophy 2B (autosomal recessive) |
| Synonyms: |
FER1L1 |
| Synonyms name: |
fer-1-like family member 1 |
| Locus: |
2p13, 2 |
| Discovery year: |
1994-03-24 |
| GenBank acession: |
AF075575 |
| Entrez gene record: |
8291 |
| Pubmed identfication: |
8320700 |
| RefSeq identity: |
NM_003494 |
| Classification: |
Ferlin family |
| Havana BLAST/BLAT: |
OTTHUMG00000129757 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_845 |