| Long name: |
ALEXA FLUOR 488 Conjugated, Angiotensin II Type 1 Receptor Antibody |
| Also known as: |
Anti-Angiotensin II Type 1 Receptor PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Angiotensin II Type 1 Receptor |
| Specificity: |
This is a highly specific antibody against Angiotensin II Type 1 Receptor |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AT1R |
| Gene ID Number: |
185 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Additional variants have been described but their full-length nature has not been determined, At least five transcript variants have been described for this gene, It acts through at least two types of receptors, It is an important effector controlling blood pressure and volume in the cardiovascular system, It was previously thought that a related gene, The entire coding sequence is contained in the terminal exon and is present in all transcript variants, This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II, This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium, [provided by RefSeq], denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans, Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
AT1 AT2R1 AGTR1A AT2R1A HAT1R AG2S AT2R1B AT1B AGTR1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Angiotensin II 1 Receptor Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Angiotensin II 1 Receptor |
| Short name: |
Angiotensin II 1 Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Angiotensin II classification 1 Receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
337 |
| Gene: |
AGTR1B |
More about : AGTR1B |
| Long gene name: |
angiotensin II receptor type 1 |
| Synonyms gene name: |
angiotensin receptor 1B |
| Locus: |
3q24 |
| Discovery year: |
1992-08-25 |
| GenBank acession: |
M87290 |
| Entrez gene record: |
185 |
| Pubmed identfication: |
1550596 |
| Classification: |
Angiotensin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000159503 |