| Long name: |
HRP Conjugated, GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GSK3 Alpha/Beta Tyr279+Tyr216 |
| Specificity: |
This is a highly specific antibody against GSK3 Alpha/Beta Tyr279+Tyr216 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr279+Tyr216 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
250-300/483 |
| Subcellular location: |
Cell membrane, Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha/Beta around the phosphorylation site of Tyr279/Tyr216 |
| Gene ID number: |
29312932 |
| Swiss Prot: |
P49840 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
APC and AXIN1, CTNNB1/beta-catenin, Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis, Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease, In Wnt signaling, Is necessary for the establishment of neuronal polarity and axon outgrowth, May also mediate the development of insulin resistance by regulating activation of transcription factors, May be involved in the regulation of replication in pancreatic beta-cells, Regulates glycogen metabolism in liver, Requires primed phosphorylation of the majority of its substrates, Through phosphorylation of the anti-apoptotic protein MCL1, Wnt signaling and regulation of transcription factors and microtubules, but not in muscle, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), may control cell apoptosis in response to growth factors deprivation, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin, Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
GSK-3 alpha, GSK3A, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase-3 alpha |
| Description: |
Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
GSK3 Alpha/Beta(Tyr279+Tyr216) Conjugated |
| Short name: |
Conjugated, GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, GSK3 a/b(Tyr279+Tyr216) (Antibody to) |
| Alternative technique: |
antibodies |