| Long name: |
4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (Pten), Recombinant Mouse Phosphatidylinositol 3 |
| Alternative names: |
Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatidylinositol 3, mitochondrial PTENalpha, mutated in multiple advanced cancers 1, phosphatase and tensin homolog, phosphatidylinositol 3, phosphatidylinositol-3, 4, 4, 4, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, phosphatidylinositol 3 |
| Gene name: |
Pten |
| Other gene names: |
2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, MMAC1, Mmac1, Pten, TEP1, Pten |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, coli, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(Pten) is a recombinant protein expressed in E, Phosphatidylinositol 3 |
| Product category: |
Recombinant Proteins |
| Expression system: |
coli, E |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Test: |
A/J, BALB/c, Mainly in phosphorylation by specific phosphatases, Mouse are mature after 40 days for females and 55 days for males, Mouse , SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, pH or protein, The duality of this product lies in it's dual specificity to the gene, mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
4, 5-trisphosphate 3-phosphatase protein phosphatase PTEN (Pten), Phosphatidylinositol 3 |
| Short name: |
4, 5-trisphosphate 3-phosphatase -specificity protein phosphatase PTEN (Pten), Mouse Phosphatidylinositol 3 |
| Technique: |
mouses, Mouse |
| Label: |
dual |
| Species: |
Mouses, Mouse |
| Alternative name: |
4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase phosphatase and tensin homolog (phosphatase and tensin homolog), Mouse Phosphatidylinositol 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
10q23del and BZS and CWS1 and DEC and GLM2 and MHAM and MMAC1 and PTEN1 and TEP1, PTEN and IDBG-637256 and ENSBTAG00000009498 and 540786, PTEN and IDBG-81409 and ENSG00000171862 and 5728, Pten and IDBG-158878 and ENSMUSG00000013663 and 19211, nuclei, phosphatidylinositol-3, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001525 and angiogenesis and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0002902 and regulation of B cell apoptotic process and biological process this GO :0004438 and phosphatidylinositol-3-phosphatase activity and molecular function this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007092 and activation of mitotic anaphase-promoting complex activity and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007270 and neuron-neuron synaptic transmission and biological process this GO :0007416 and synapse assembly and biological process this GO :0007417 and central nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0007611 and learning or memory and biological process this GO :0007613 and memory and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009749 and response to glucose and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0010033 and response to organic substance and biological process this GO :0010035 and response to inorganic substance and biological process this GO :0010043 and response to zinc ion and biological process this GO :0010975 and regulation of neuron projection development and biological process this GO :0010997 and anaphase-promoting complex binding and molecular function this GO :0014067 and negative regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016314 and phosphatidylinositol-3, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004438 : phosphatidylinositol-3-phosphatase activity and also this GO :0004721 : phosphoprotein phosphatase activity and also this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008138 : protein tyrosine/serine/threonine phosphatase activity and also this GO :0008289 : lipid binding and also this GO :0010997 : anaphase-promoting complex binding and also this GO :0016314 : phosphatidylinositol-3, this GO :0004438 : phosphatidylinositol-3-phosphatase activity, this GO :0004721 : phosphoprotein phosphatase activity, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005515 : protein binding, this GO :0008138 : protein tyrosine/serine/threonine phosphatase activity, this GO :0008289 : lipid binding, this GO :0010997 : anaphase-promoting complex binding, this GO :0016314 : phosphatidylinositol-3, this GO :0016791 : phosphatase activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0030165 : PDZ domain binding, this GO :0051717 : inositol-1, this GO :0051800 : phosphatidylinositol-3, 3, 3, 3, 4, 4, 4, 4, 4, 4, 4-bisphosphate 3-phosphatase activity, 4-bisphosphate 3-phosphatase activity, 4-bisphosphate 3-phosphatase activity and molecular function this GO :0051895 and negative regulation of focal adhesion assembly and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060024 and rhythmic synaptic transmission and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060074 and synapse maturation and biological process this GO :0060134 and prepulse inhibition and biological process this GO :0060179 and male mating behavior and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0060736 and prostate gland growth and biological process this GO :0060997 and dendritic spine morphogenesis and biological process this GO :0061002 and negative regulation of dendritic spine morphogenesis and biological process this GO :0090071 and negative regulation of ribosome biogenesis and biological process this GO :0090344 and negative regulation of cell aging and biological process this GO :0090394 and negative regulation of excitatory postsynaptic membrane potential and biological process this GO :0097105 and presynaptic membrane assembly and biological process this GO :0097107 and postsynaptic density assembly and biological process this GO :2000060 and positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :2000134 and negative regulation of G1/S transition of mitotic cell cycle and biological process this GO :2000463 and positive regulation of excitatory postsynaptic membrane potential and biological process this GO :2000808 and negative regulation of synaptic vesicle clustering and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, 5-tetrakisphosphate 3-phosphatase activity, 5-tetrakisphosphate 3-phosphatase activity and also this GO :0051800 : phosphatidylinositol-3, 5-tetrakisphosphate 3-phosphatase activity and molecular function this GO :0051726 and regulation of cell cycle and biological process this GO :0051800 and phosphatidylinositol-3, 5-trisphosphate 3-phosphatase activity, 5-trisphosphate 3-phosphatase activity and also this GO :0016791 : phosphatase activity and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0030165 : PDZ domain binding and also this GO :0051717 : inositol-1, 5-trisphosphate 3-phosphatase activity and molecular function this GO :0016477 and cell migration and biological process this GO :0016605 and PML body and cellular component this GO :0016791 and phosphatase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0021542 and dentate gyrus development and biological process this GO :0021955 and central nervous system neuron axonogenesis and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0030336 and negative regulation of cell migration and biological process this GO :0031175 and neuron projection development and biological process this GO :0031642 and negative regulation of myelination and biological process this GO :0031647 and regulation of protein stability and biological process this GO :0031658 and negative regulation of cyclin-dependent protein kinase activity involved in G1/S and biological process this GO :0032286 and central nervous system myelin maintenance and biological process this GO :0032355 and response to estradiol and biological process this GO :0032535 and regulation of cellular component size and biological process this GO :0033032 and regulation of myeloid cell apoptotic process and biological process this GO :0033198 and response to ATP and biological process this GO :0033555 and multicellular organismal response to stress and biological process this GO :0035176 and social behavior and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035749 and myelin sheath adaxonal region and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042711 and maternal behavior and biological process this GO :0042995 and cell projection and cellular component this GO :0043005 and neuron projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043197 and dendritic spine and cellular component this GO :0043220 and Schmidt-Lanterman incisure and cellular component this GO :0043491 and protein kinase B signaling and biological process this GO :0043542 and endothelial cell migration and biological process this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045211 and postsynaptic membrane and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045475 and locomotor rhythm and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :0046621 and negative regulation of organ growth and biological process this GO :0046685 and response to arsenic-containing substance and biological process this GO :0046855 and inositol phosphate dephosphorylation and biological process this GO :0046856 and phosphatidylinositol dephosphorylation and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048738 and cardiac muscle tissue development and biological process this GO :0048853 and forebrain morphogenesis and biological process this GO :0048854 and brain morphogenesis and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050765 and negative regulation of pha this GO cytosis and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050821 and protein stabilization and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051717 and inositol-1, phosphatase and tensin homolog |
| Identity: |
9588 |
| Gene: |
PTEN |
More about : PTEN |
| Long gene name: |
phosphatase and tensin homolog |
| Synonyms gene: |
BZS MHAM |
| Synonyms: |
MMAC1 TEP1 PTEN1 |
| Synonyms name: |
mutated in multiple advanced cancers 1 |
| Locus: |
10q23, 31 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
U92436 |
| Entrez gene record: |
5728 |
| Pubmed identfication: |
9090379 |
| RefSeq identity: |
NM_000314 |
| Classification: |
Phosphoinositide phosphatases PTEN protein phosphatases C2 tensin-type domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018688 |
| Locus Specific Databases: |
LRG_311 |