| Long name: |
ALEXA FLUOR 488 Conjugated, Menin Polyclonal Antibody |
| Also known as: |
Anti-Menin PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Menin |
| Specificity: |
This is a highly specific antibody against Menin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
560-612/615 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Menin |
| Gene ID Number: |
4221 |
| Swiss Prot: |
O00255 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds to the TERT promoter and represses telomerase expression, Functions as a transcriptional regulator, May be involved in DNA repair, May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity), Plays a role in TGFB1-mediated inhibition of cell-proliferation, Positively regulates HOXC8 and HOXC6 gene expression, Represses JUND-mediated transcriptional activation on AP1 sites, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4), as well as that mediated by NFKB subunit RELA, possibly regulating SMAD3 transcriptional activity, Essential component of a MLL/SET1 histone methyltransferase (HMT) complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Menin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Menin |
| Short name: |
Menin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Menin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7010 |
| Gene: |
MEN1 |
More about : MEN1 |
| Long gene name: |
menin 1 |
| Synonyms gene name: |
multiple endocrine neoplasia I |
| Synonyms name: |
menin |
| Locus: |
11q13 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
U93236 |
| Havana BLAST/BLAT: |
OTTHUMG00000045366 |
| Locus Specific Databases: |
UMD Locus Specific Databases LRG_509 |