| Long name: |
LCAT Primary Polyclonal Antibody |
| Also known as: |
LCAT PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LCAT |
| Specificity: |
This is a highly specific antibody against LCAT |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
170-220/440 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LCAT |
| Gene ID number: |
3931 |
| Swiss Prot: |
P04180 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also produced in the brain by primary astrocytes, Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines, Required for remodeling high-density lipoprotein particles into their spherical forms, Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs), The cholesterol ester is then transported back to the liver, Together with APOE and the cholesterol transporter ABCA1, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels, nascent lipoproteins, plays a key role in the maturation of glial-derived, Central enzyme in the extracellular metabolism of plasma lipoproteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
LCAT, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, Phosphatidylcholine-sterol acyltransferase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LCAT |
| Short name: |
LCAT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LCAT (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6522 |
| Gene: |
LCAT |
More about : LCAT |
| Long gene name: |
lecithin-cholesterol acyltransferase |
| Synonyms name: |
phosphatidylcholine--sterol O-acyltransferase |
| Locus: |
16q22, 1 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
3931 |
| Havana BLAST/BLAT: |
OTTHUMG00000137551 |