WNK3 protein Antibody, Biotin Conjugated

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Catalog number: bs-1945R-Biotin
Price: 333 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: WNK3 protein Antibody, Biotin Conjugated
Quantity: 0.1ml
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Long name: Biotin Conjugated, WNK3 protein Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Biotinylated
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: WNK3 protein
Specificity: This is a highly specific antibody against WNK3 protein
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 475-520/1800
Subcellular location: Cytoplasm
Source: KLH conjugated synthetic peptide derived from human WNK3 protein
Gene ID number: 65267
Swiss Prot: Q9BYP7
Tested applications: IHC-P
Recommended dilutions: IHC-P(1:100-500)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: According to PubMed:19470686, Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively, Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway, Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner, Isoform 1, Phosphorylates WNK4, Regulates the phosphorylation of SLC12A1 and SLC12A2, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7, cell signaling, isoform 1 inhibits the activity of SLC12A3, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, survival and proliferation, Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Properties: Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: WNK3 protein Conjugated
Short name: Conjugated, WNK3 protein Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Biotin
Alternative name: biotinilated coupled, WNK lysine deficient protein kinase 3 protein (Antibody to)
Alternative technique: antibodies
Alternative to gene target: Cell surfaces, WNK3 and IDBG-637533 and ENSBTAG00000023182 and, WNK3 and IDBG-71035 and ENSG00000196632 and 65267, Wnk3 and IDBG-178902 and ENSMUSG00000041245 and 279561, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010800 and positive regulation of peptidyl-threonine phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019869 : chloride channel inhibitor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019869 : chloride channel inhibitor activity, transferring phosphorus-containing groups and molecular function this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0032414 and positive regulation of ion transmembrane transporter activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process this GO :2000021 and regulation of ion homeostasis and biological process this GO :2000651 and positive regulation of sodium ion transmembrane transporter activity and biological process this GO :2000682 and positive regulation of rubidium ion transport and biological process this GO :2000688 and positive regulation of rubidium ion transmembrane transporter activity and biological process, WNK lysine deficient protein kinase 3
Identity: 14543
Gene: WNK3 | More about : WNK3
Long gene name: WNK lysine deficient protein kinase 3
Synonyms gene: PRKWNK3
Synonyms gene name: lysine deficient 3 , protein kinase
Locus: Xp11, 22
Discovery year: 2001-02-07
GenBank acession: AJ409088
Entrez gene record: 65267
RefSeq identity: NM_020922
Havana BLAST/BLAT: OTTHUMG00000021626
Locus Specific Databases: Mental Retardation database

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