WNK3 protein Antibody, ALEXA FLUOR 488

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Catalog number: bs-1945R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: WNK3 protein Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, WNK3 protein Polyclonal Antibody
Also known as: Anti-WNK3 protein PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: WNK3 protein
Specificity: This is a highly specific antibody against WNK3 protein
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 475-520/1800
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WNK3 protein
Gene ID Number: 65267
Swiss Prot: Q9BYP7
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: According to PubMed:19470686, Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively, Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway, Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner, Isoform 1, Phosphorylates WNK4, Regulates the phosphorylation of SLC12A1 and SLC12A2, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7, cell signaling, isoform 1 inhibits the activity of SLC12A3, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, survival and proliferation, Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the WNK3 protein Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: WNK3 protein
Short name: WNK3 protein Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, WNK lysine deficient protein kinase 3 protein (Antibody to)
Alternative technique: antibodies
Alternative to gene target: Cell surfaces, WNK3 and IDBG-637533 and ENSBTAG00000023182 and, WNK3 and IDBG-71035 and ENSG00000196632 and 65267, Wnk3 and IDBG-178902 and ENSMUSG00000041245 and 279561, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010800 and positive regulation of peptidyl-threonine phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019869 : chloride channel inhibitor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019869 : chloride channel inhibitor activity, transferring phosphorus-containing groups and molecular function this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0032414 and positive regulation of ion transmembrane transporter activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process this GO :2000021 and regulation of ion homeostasis and biological process this GO :2000651 and positive regulation of sodium ion transmembrane transporter activity and biological process this GO :2000682 and positive regulation of rubidium ion transport and biological process this GO :2000688 and positive regulation of rubidium ion transmembrane transporter activity and biological process, WNK lysine deficient protein kinase 3
Identity: 14543
Gene: WNK3 | More about : WNK3
Long gene name: WNK lysine deficient protein kinase 3
Synonyms gene: PRKWNK3
Synonyms gene name: lysine deficient 3 , protein kinase
Locus: Xp11, 22
Discovery year: 2001-02-07
GenBank acession: AJ409088
Entrez gene record: 65267
RefSeq identity: NM_020922
Havana BLAST/BLAT: OTTHUMG00000021626
Locus Specific Databases: Mental Retardation database

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