ZAP70 Antibody

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Catalog number: bs-1942R
Price: 263 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: ZAP70 Antibody
Quantity: 0.1ml
Other quantities: 0.1mg 406€ 1 vial 532€ 100ug 370€ 100ul 426€
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More details :

Long name: ZAP70 Primary Polyclonal Antibody
Also known as: ZAP70 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: ZAP70
Specificity: This is a highly specific antibody against ZAP70
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZAP-70
Gene ID number: 7535
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Jul 2008], Lck and Fyn, Mutations in this gene cause selective T-cell defect, This enzyme, This enzyme is also essential for thymocyte development, Two transcript variants that encode different isoforms have been found for this gene, [provided by RefSeq, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells, and it plays a role in T-cell development and lymphocyte activation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, This gene encodes an enzyme belonging to the protein tyrosine kinase family
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: 70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, SRK, STD, Syk-related tyrosine kinase, TZK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase ZAP-70, ZAP 70, ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase domains}, ZAP70, ZAP70_HUMAN, zeta-associated protein 70, ZAP-70
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: ZAP70
Short name: ZAP70 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: zeta-chain (TCR) associated protein kinase 70kDa (Antibody to)
Alternative technique: antibodies
Alternative to gene target: Cell surfaces, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, this GO :0001772 and immunological synapse and cellular component this GO :0001784 and phosphotyrosine binding and molecular function this GO :0002250 and adaptive immune response and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0016772 and transferase activity, this GO :0001784 : phosphotyrosine binding, this GO :0001784 : phosphotyrosine binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0043366 and beta selection and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045061 and thymic T cell selection and biological process this GO :0045121 and membrane raft and cellular component this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0070489 and T cell aggregation and biological process this GO :0072678 and T cell migration and biological process, zeta-chain (TCR) associated protein kinase 70kDa
Identity: 12858
Gene: ZAP70 | More about : ZAP70
Long gene name: zeta chain of T-cell receptor associated protein kinase 70
Synonyms gene: SRK
Synonyms gene name: zeta-chain (TCR) associated protein kinase (70 kD) zeta-chain (TCR) associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70
Synonyms: ZAP-70 STD
Synonyms name: tyrosine-protein kinase ZAP-70
Locus: 2q11, 2
Discovery year: 1995-05-16
GenBank acession: L05148
Entrez gene record: 7535
Pubmed identfication: 1423621
RefSeq identity: NM_001079
Classification: SH2 domain containing
Havana BLAST/BLAT: OTTHUMG00000153060
Locus Specific Databases: ZAP70base: Mutation registry for autosomal recessive ZAP70 immunodeficiency LRG_126

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