| Long name: |
ALEXA FLUOR 488 Conjugated, TLR1 Polyclonal Antibody |
| Also known as: |
Anti-TLR1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TLR1 |
| Specificity: |
This is a highly specific antibody against TLR1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLR1 |
| Gene ID Number: |
7096 |
| Swiss Prot: |
Q15399 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts via MYD88 and TRAF6, Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides, Specifically recognizes diacylated and triacylated lipopeptides, cytokine secretion and the inflammatory response (By similarity), leading to NF-kappa-B activation, Participates in the innate immune response to microbial agents |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
rsc786 KIAA0012 CD281 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TLR1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TLR1 |
| Short name: |
TLR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, toll-like receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD281 and rsc786 and TIL and TIL, LPRS5, Plasma membranes, TLR1 and IDBG-13627 and ENSG00000174125 and 7096, Tlr1 and IDBG-165889 and ENSMUSG00000044827 and 21897, protein heterodimerization activity, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0034130 and toll-like receptor 1 signaling pathway and biological process this GO :0035354 and Toll-like receptor 1-Toll-like receptor 2 protein complex and cellular component this GO :0042116 and macrophage activation and biological process this GO :0042495 and detection of triacyl bacterial lipopeptide and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045410 and positive regulation of interleukin-6 biosynthetic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050707 and regulation of cytokine secretion and biological process this GO :0071727 and cellular response to triacyl bacterial lipopeptide and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0046982 : protein heterodimerization activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0046982 : protein heterodimerization activity, toll-like receptor 1 |
| Identity: |
11847 |
| Gene: |
TLR1 |
More about : TLR1 |
| Long gene name: |
toll like receptor 1 |
| Synonyms gene name: |
toll-like receptor 1 |
| Locus: |
4p14 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88540 |
| Entrez gene record: |
7096 |
| Pubmed identfication: |
9435236 7584026 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000160413 |