MMP-8 Antibody, ALEXA FLUOR 647

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Catalog number: bs-1913R-A647
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: MMP-8 Antibody, ALEXA FLUOR 647
Quantity: 100ul
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Long name: ALEXA FLUOR 647 Conjugated, MMP-8 Polyclonal Antibody
Also known as: Anti-MMP-8 PAb ALEXA FLUOR 647
Category: Conjugated Primary Antibodies
Conjugated with: 647, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: MMP-8
Specificity: This is a highly specific antibody against MMP-8
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 262-312/467
Subcellular location: Secreted, Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MMP8
Gene ID Number: 4317
Swiss Prot: P22894
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, II, III, MMP13, MMP8 degrades fibrillar collagens types I, MMP8 is heavily glycosylated, MMP8 is very similar to MMP1, Most cell types do not produce MMP8, The human MMP8 gene has the chromosomal location of 11q22, The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, The zymogen is quickly activated to the 64 Kd form, Until recently, aggrecan, and the zymogen has a mass of 85 Kd, and this breaks down to a cascade of active forms, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8, it was thought that MMP8 was produced exclusively by neutrophils, serpins and alpha 2 macroglobulin, sharing 57 % amino acid identity, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen, which then denature to gelatin at body temperature, 2-22, 3, Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 650nm/665nm
Synonyms: CLG1, MMP-8, MMP8, Matrix metalloproteinase-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL, HNC
Properties: ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MMP-8 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 647, Alexa Fluor
Gene target: MMP-8
Short name: MMP-8 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 647
Alternative name: ALEXA FLUOR 647, MMP-8 (Antibody to)
Alternative technique: antibodies

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