| Long name: |
Cy3 Conjugated, TGF Beta R3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TGF Beta R3 |
| Specificity: |
This is a highly specific antibody against TGF Beta R3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TGFBR3 |
| Gene ID number: |
7049 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII, It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form, It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems, Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2, TGF beta III receptor, TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor, TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone, TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling, TGFB2, The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins, There are 3 forms encoded by separate genes TGFB1, These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, adhesion, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration, and TGFB3, and extracellular matrix production, can function as an inhibin coreceptor with ActRII, cell cycle progression, cellular migration, including cell differentiation, nonredundant role in TGF beta signaling, or beta glycan, type III (TGF beta III receptor) has been identified, Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
BGCAN, Betaglycan, Betaglycan proteoglycan, TGF beta Receptor III, TGF beta receptor type 3, TGF beta receptor type III, TGFB R3, TGFBR 3, TGFBR3, TGFR 3, TGFR3, Transforming Growth Factor Beta Receptor III, Transforming growth factor beta receptor III betaglycan 300kDa, Beta glycan |
| Properties: |
1 of the TGF Beta R3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TGF Beta R3 Conjugated |
| Short name: |
Conjugated, TGF Beta R3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, TGF b R3 (Antibody to) |
| Alternative technique: |
antibodies |