| Long name: |
MKP-2/DUSP4 Primary Polyclonal Antibody |
| Also known as: |
MKP-2/DUSP4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MKP-2/DUSP4 |
| Specificity: |
This is a highly specific antibody against MKP-2/DUSP4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MKP-2 |
| Gene ID number: |
1846 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, ERK2 and JNK, In addition, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene product inactivates ERK1, Two alternatively spliced transcript variants, and different modes of inducibility of their expression by extracellular stimuli, and is localized in the nucleus, different tissue distribution and subcellular localization, encoding distinct isoforms, have been observed for this gene, is expressed in a variety of tissues, multiple polyadenylation sites have been reported, p38), which is associated with cellular proliferation and differentiation, DUSP4 is a member of the dual specificity protein phosphatase subfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DUSP 4, Dual specicity phosphatase 4, Dual specicity protein phosphatase 4, Dual specicity protein phosphatase hVH2, HVH 2, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, Mitogen activated protein kinase phosphatase 2, Serine/threonine specic protein phosphatase, TYP, VH 2, VH1 homologous phosphatase 2, VH2, Mitogen activated protein kinase phosphatase 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MKP-2/DUSP4 |
| Short name: |
MKP-2/DUSP4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MKP-2/DUSP4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3070 |
| Gene: |
DUSP4 |
More about : DUSP4 |
| Long gene name: |
dual specificity phosphatase 4 |
| Synonyms: |
HVH2 MKP-2 TYP |
| Synonyms name: |
VH1 homologous phosphatase 2 MAP kinase phosphatase 2 |
| Locus: |
8p12 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
U21108 |
| Entrez gene record: |
1846 |
| Pubmed identfication: |
7535768 9205128 |
| RefSeq identity: |
NM_001394 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000133395 |