| Long name: |
ALEXA FLUOR 594 Conjugated, Notch3/4 Polyclonal Antibody |
| Also known as: |
Anti-Notch3/4 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Notch3/4 |
| Specificity: |
This is a highly specific antibody against Notch3/4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse Notch3 |
| Gene ID Number: |
4854 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot), It affects the implementation of differentiation, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus, proliferation and apoptotic programs, NOTCH3 functions as a receptor for membrane-bound ligands Jagged1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CADASIL, CASIL, Notch homolog 3, INT 3, INT3, MGC74442, NOTC4_HUMAN, NOTCH 3, NOTCH-3, NOTCH-4, NOTCH3, NOTCH4 protein, Neurogenic locus notch homolog protein 1, Neurogenic locus notch homolog protein 3, Neurogenic locus notch homolog protein 4, Notch 4 intracellular domain, Notch homolog 4, hNotch 4, hNotch4 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Notch3/4 |
| Short name: |
Notch3/4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Notch3/4 (Antibody to) |
| Alternative technique: |
antibodies |