| Long name: |
Cy3 Conjugated, CCL21/6Ckine Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCL21/6Ckine |
| Specificity: |
This is a highly specific antibody against CCL21/6Ckine |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
70-120/134 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human CCL21 |
| Gene ID number: |
6366 |
| Swiss Prot: |
O00585 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4, Chemotactic in vitro for thymocytes and activated T-cells, May play a role in mediating homing of lymphocytes to secondary lymphoid organs, Shows preferential activity towards naive T-cells, but not for B-cells, macrophages, or neutrophils, Inhibits hemopoiesis and stimulates chemotaxis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
SLC exodus-2 TCA4 CKb9 6Ckine ECL |
| Properties: |
1 of the CCL21/6Ckine Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCL21/6Ckine Conjugated |
| Short name: |
Conjugated, CCL21/6Ckine Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, chemokine (C-C motif) ligand 21/6Ckine (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
6Ckine and CKb9 and ECL and SCYA21 and SLC and TCA4, BT, CCL21 and IDBG-61074 and ENSG00000137077 and 6366, Extracellular, chemokine receptor binding, this GO :0001768 and establishment of T cell polarity and biological process this GO :0001771 and immunological synapse formation and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0010560 and positive regulation of glycoprotein biosynthetic process and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0031295 and T cell costimulation and biological process this GO :0031529 and ruffle organization and biological process this GO :0031732 and CCR7 chemokine receptor binding and molecular function this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0035759 and mesangial cell-matrix adhesion and biological process this GO :0042379 and chemokine receptor binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048260 and positive regulation of receptor-mediated endocytosis and biological process this GO :0048469 and cell maturation and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097026 and dendritic cell dendrite assembly and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000406 and positive regulation of T cell migration and biological process this GO :2000529 and positive regulation of myeloid dendritic cell chemotaxis and biological process this GO :2000548 and negative regulation of dendritic cell dendrite assembly and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0031732 : CCR7 chemokine receptor binding and also this GO :0042379 : chemokine receptor binding, this GO :0031732 : CCR7 chemokine receptor binding, this GO :0042379 : chemokine receptor binding, 26536 and IDBG-635977 and ENSBTAG00000010161 and 511112, chemokine (C-C motif) ligand 21 |
| Identity: |
10620 |
| Gene: |
CCL21 |
More about : CCL21 |
| Long gene name: |
C-C motif chemokine ligand 21 |
| Synonyms gene: |
SCYA21 |
| Synonyms gene name: |
member 21 chemokine (C-C motif) ligand 21 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms name: |
beta chemokine exodus-2 secondary lymphoid tissue chemokine Efficient Chemoattractant for Lymphocytes |
| Locus: |
9p13, 3 |
| Discovery year: |
1997-04-10 |
| GenBank acession: |
AB002409 |
| Entrez gene record: |
6366 |
| Pubmed identfication: |
9235955 |
| RefSeq identity: |
NM_002989 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000019838 |