| Long name: |
ALEXA FLUOR 594 Conjugated, PAK3 (Ser139) Polyclonal Antibody |
| Also known as: |
Anti-PAK3 Ser139 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PAK3 Ser139 |
| Specificity: |
This is a highly specific antibody against PAK3 Ser139 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser139 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PAK3 around the phosphorylation site of (Ser139) |
| Gene ID Number: |
5063 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), CDC42 and RAC1, PAK 2, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, The three most common isoforms are PAK 1, These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, and PAK 3 (also known as alpha PAK, and beta PAK, and caspase mediated proteolytic cleavage, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, catalyzed by Cdc42, gamma PAK, interaction with Src homology 3 (SH3) domains, is required for activation of PAK, members of which are activated by small molecular weight GTPases, respectively), P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hPAK3 bPAK |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
PAK3 (Ser139) |
| Short name: |
PAK3 (Ser139) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, PAK3 (Ser139) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8592 |
| Gene: |
PAK3 |
More about : PAK3 |
| Long gene name: |
p21 (RAC1) activated kinase 3 |
| Synonyms gene: |
MRX30 MRX47 |
| Synonyms gene name: |
X-linked 47 p21 (CDKN1A)-activated kinase 3 p21 protein (Cdc42/Rac)-activated kinase 3 , mental retardation |
| Locus: |
Xq23 |
| Discovery year: |
1998-03-25 |
| GenBank acession: |
AF068864 |
| Entrez gene record: |
5063 |
| Pubmed identfication: |
8826460 9731525 |
| RefSeq identity: |
NM_002578 |
| Classification: |
X-linked mental retardation |
| Havana BLAST/BLAT: |
OTTHUMG00000022202 |