| Long name: |
Cy3 Conjugated, Estrogen Receptor alpha (Y537) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Estrogen Receptor alpha Tyr537 |
| Specificity: |
This is a highly specific antibody against Estrogen Receptor alpha Tyr537 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr537 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ER alpha around the phosphorylation site of Tyr537 |
| Gene ID number: |
2099 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ER Alpha and ER Beta, ER Alpha and ER Beta have been shown to be differentially activated by various ligands, In most cells, The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), The carboxy terminal region of the estrgen receptor contains the ligand binding domain, The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes, Two forms of estrogen receptor have been identified, and the DNA binding domain is centrally located, hPR-B functions as a transcriptional activator of progesterone-responsive gene, the amino terminus serves as the transactivation domain, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors, which arise from alternative splicing, Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
Atherosclerosis, DKFZp686N23123, ER, ER Alpha, ER alpha Tyr537, ER alpha Y537, ER alpha Y537, ER-alpha, ER[a], ERalpha, ESR, ESR1, ESR1_HUMAN, ESR2, ESRA, Era, Estr, Estradiol Receptor-alpha, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor alpha Tyr537, Estrogen Receptor alpha Y537, Estrogen receptor 1 alpha, Estrogen receptor alpha, Estrogen resistance, HDL cholesterol, Myocardial infarction, NR3A1, Nuclear receptor subfamily 3 group A member 1, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, augmented response of, included, included, included, included, p-ER alpha Tyr537, p-ER alpha Y537, susceptibility to, susceptibility to, to hormone replacement, ER alpha Tyr537 |
| Properties: |
1 of the Estrogen Receptor alpha (Y537) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Estrogen Receptor alpha (Y537) Conjugated |
| Short name: |
Conjugated, Estrogen Receptor alpha (Y537) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Estrogen Receptor a (Y537) (Antibody to) |
| Alternative technique: |
antibodies |