| Long name: |
SATB1 Primary Polyclonal Antibody |
| Also known as: |
SATB1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SATB1 |
| Specificity: |
This is a highly specific antibody against SATB1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-750/764 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from mouse SATB1 |
| Gene ID number: |
20230 |
| Swiss Prot: |
Q60611 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers, Binds to DNA at special AT-rich sequences, Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma, Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes, Plays a role in chromatin organization and nuclear architecture during apoptosis (By similarity), Thought to recognize the sugar-phosphate structure of double-stranded DNA, Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, and beta- and gamma-globin genes regulation during erythroid differentiation, at nuclear matrix- or scaffold-associated regions, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling, the consensus SATB1-binding sequence (CSBS), Required for the switching of fetal globin species |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
2610306G12Rik, DNA-binding protein SATB1, Satb1, Special AT-rich sequence-binding protein 1, AW413156 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SATB1 |
| Short name: |
SATB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SATB homeobox 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0008544 and epidermis development and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016571 and histone methylation and biological process this GO :0016605 and PML body and cellular component this GO :0042110 and T cell activation and biological process this GO :0043367 and CD4-positive, SATB1 and IDBG-21555 and ENSG00000182568 and 6304, SATB1 and IDBG-640809 and ENSBTAG00000021158 and 516952, Satb1 and IDBG-190608 and ENSMUSG00000023927 and 20230, alpha-beta T cell differentiation and biological process this GO :0043374 and CD8-positive, alpha-beta T cell differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0050798 and activated T cell proliferation and biological process this GO :0060004 and reflex and biological process, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000785 and chromatin and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005720 and nuclear heterochromatin and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, SATB homeobox 1 |
| Identity: |
10541 |
| Gene: |
SATB1 |
More about : SATB1 |
| Long gene name: |
SATB homeobox 1 |
| Synonyms gene name: |
special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA) |
| Locus: |
3p24, 3 |
| Discovery year: |
1994-05-03 |
| Entrez gene record: |
6304 |
| Pubmed identfication: |
1505028 |
| RefSeq identity: |
NM_001131010 |
| Classification: |
CUT class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000129890 |