| Long name: |
APOBEC3G Primary Polyclonal Antibody |
| Also known as: |
APOBEC3G PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APOBEC3G |
| Specificity: |
This is a highly specific antibody against APOBEC3G |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
235-265/384 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APOBEC3G |
| Gene ID number: |
60489 |
| Swiss Prot: |
Q9HC16 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), Exhibits potent antiviral activity against vif-deficient HIV-1, May inhibit the mobility of LTR and non-LTR retrotransposons, Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA, The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, equine infectious anemia virus (EIAV), hepatitis B virus (HBV), it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA, together exert efficient antiretroviral effects in infected target cells, xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV), DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APOBEC-related cytidine deaminase, APOBEC-related protein, APOBEC-related protein 9, APOBEC3G, ARCD, ARP-9, ARP9, CEM-15, CEM15, DNA dC->, Deoxycytidine deaminase, MDS019, bK150C2, dJ494G10, 1, 7, A3G, dU-editing enzyme APOBEC-3G |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APOBEC3G |
| Short name: |
APOBEC3G Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APOBEC3G (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17357 |
| Gene: |
APOBEC3G |
More about : APOBEC3G |
| Long gene name: |
apolipoprotein B mRNA editing enzyme catalytic subunit 3G |
| Synonyms gene name: |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| Synonyms: |
CEM15 MDS019 dJ494G10, 1 FLJ12740 bK150C2, 7 |
| Synonyms name: |
DNA dC->, dU-editing enzyme APOBEC-3G |
| Locus: |
22q13, 1 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
AF182420 |
| Entrez gene record: |
60489 |
| Pubmed identfication: |
11863358 |
| RefSeq identity: |
NM_021822 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000151081 |