| Long name: |
HRP Conjugated, DTX3L Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DTX3L |
| Specificity: |
This is a highly specific antibody against DTX3L |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
720-738/740 |
| Source: |
KLH conjugated synthetic peptide derived from human DTX3L |
| Gene ID number: |
151636 |
| Swiss Prot: |
Q8TDB6 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In concert with PARP9, Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation, PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, Protects cells exposed to DNA-damaging agents, The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me), UIMC1/RAP80, and BRCA1 to DNA damage sites, in response to DNA damage, plays a role in PARP1-dependent DNA damage repair, Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
BBAP |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
DTX3L Conjugated |
| Short name: |
DTX3L Antibody Conjugated |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, DTX3L (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30323 |
| Gene: |
DTX3L |
More about : DTX3L |
| Long gene name: |
deltex E3 ubiquitin ligase 3L |
| Synonyms gene name: |
deltex 3-like (Drosophila) |
| Synonyms name: |
rhysin 2 |
| Locus: |
3q21, 1 |
| Discovery year: |
2004-12-03 |
| Entrez gene record: |
151636 |
| Pubmed identfication: |
12670957 22411408 |
| RefSeq identity: |
NM_138287 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000159524 |