| Also known as: |
CD28 |
| Other names: |
CD28 antigen, CD28 molecule, CD_antigen: CD28, T-cell-specific surface glycoprotein CD28, T-cell-specific surface glycoprotein CD28, TP44, T-cell-specific surface glycoprotein CD28 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD28 |
| Other gene names: |
CD28, N/A, Tp44, CD28 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
37, 51 |
| Host organism: |
Syrian hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 45 kD homodimeric protein expressed by thymocytes, mature T cells and NK cells, 51 reacts with extracellular domain of mouse CD28 costimulatory receptor, The hamster monoclonal antibody 37 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, pH 7, 2 micron filter sterilized, 4, Azide-free PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Avoid freeze/thaw cycles, For long-term storage aliquot and For optimal long term storage, This low endotoxin solution contains no preservative, handle under aseptic conditions, the antibody should be kept at -20 degrees Celsius, Store the antibody ats should be kept in the range of 1-7 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), Functional Assay, IHC - Frozen), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
51] CD28, Syrian Monoclonal [ 37 |
| Short name: |
51] (IgG) Mouse CD28 Antibody, Syrian hamster Monoclonal [clone 37 |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Mouses, Mouse |
| Alternative name: |
51] (Immunoglobulin G) to Mouse CD28 molecule (Antibody to), Syrian hamster monoclonal [clonality 37 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD28 and IDBG-643371 and ENSBTAG00000007445 and 281050, CD28 and IDBG-79183 and ENSG00000178562 and 940, Cd28 and IDBG-159608 and ENSMUSG00000026012 and 12487, Cell surfaces, Tp44, identical protein binding, this GO :0001772 and immunological synapse and cellular component this GO :0002020 and protease binding and molecular function this GO :0002863 and positive regulation of inflammatory response to antigenic stimulus and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042089 and cytokine biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045060 and negative thymic T cell selection and biological process this GO :0045066 and regulatory T cell differentiation and biological process this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0042802 : identical protein binding, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0042802 : identical protein binding, CD28 molecule |
| Identity: |
1653 |
| Gene: |
CD28 |
More about : CD28 |
| Long gene name: |
CD28 molecule |
| Synonyms gene name: |
CD28 antigen (Tp44) |
| Synonyms name: |
T-cell-specific surface glycoprotein |
| Locus: |
2q33, 2 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
J02988 |
| Entrez gene record: |
940 |
| Pubmed identfication: |
1355979 |
| RefSeq identity: |
NM_006139 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132878 |