| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TROVE-2 |
| Specificity: |
This antibody reacts specifically with TROVE-2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TROVE-2/SSA2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ANA-negative lupus erythematosus, La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjé, Most anti-Ro/SSA-positive sera detect not only the main protein, Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50% of patients with SLE and in up to 97% of patients with Sjqgren syndrome (2), The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2), The genes which encode the smaller and larger proteins map to human chromosomes 11p15, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1), but also a smaller Ro/SSA protein (2), neonatal lupus erythematosus, respectively (3?), subacute cutaneous lupus erythematosus (SLE), °, &fnof, 5 and 1q31, Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, ren syndrome and SLE (6) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
60 kDa Ro protein, 60 kDa SS A/Ro ribonucleoprotein, 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa ribonucleoprotein Ro, 60-KD, Autoantigen Ro/SSA, Gastric cancer multi drug resistance protein, RO 60, RO60, RO60_HUMAN, Ribonucleoprotein autoantigen SS A/Ro, Ro 60 kDa autoantigen, RoRNP, SS A, SS-A, SS-A/Ro, SSA, SSA 2, SSA2, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, Sjogren syndrome antigen A2, Sjogren syndrome antigen A2 60kD ribonucleoprotein autoantigen SS A/Ro, Sjogren syndrome antigen A2 60kDa ribonucleoprotein autoantigen SS A/Ro, TROVE 2, TROVE domain family member 2, TROVE2, bA101E13, 2, TROVE2 |
| Also known as: |
TROVE-2 Polyclonal Antibody |
| Other name: |
Anti-TROVE-2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TROVE-2 |
| Short name: |
Anti-TROVE-2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TROVE-2 (polyclonal) |
| Alternative technique: |
polyclonals |