| Long name: |
ZNF423/OAZ Primary Polyclonal Antibody |
| Also known as: |
ZNF423/OAZ PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ZNF423/OAZ |
| Specificity: |
This is a highly specific antibody against ZNF423/OAZ |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZNF423/OAZ |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
5 and 8, BMPs bind to surface receptors, Bone morphogenic proteins (BMPs), DNA-binding factor that associates with members of the Smad family of transcription factors in response to BMP2 activation, Distinct regions of OAZ, OAZ contains a BMP signaling module formed by two clusters of fingers that individually associate with either the Smads or the BMP response element, OAZ may have dual roles in signal transduction during development, OAZ specifically cooperates with the BMP-activated Smads, also enable OAZ to function as a transcriptional partner of Olf-1/EBF in olfactory epithelium and lymphocyte development, and activating transcription, are the largest group within the TGFâ, as a multiâ, growth factors superfamily and are involved in embryonic development, in binding to the CAGAC and TGGAGC boxes within the BRE, indicating that, namely Smad1, neurogenesis, or BMP response element, organogenesis and skeletal development, separate from the modules involved in BMP regulation, specifically the formation of left-right asymmetry, which then phosphorylate serine residues of specific Smad proteins to induce Smad translocation to the nucleus and transcriptional activation of BMP targeted genes, &circ, &euro, «, &ldquo, OAZ is a 30-zinc finger, zinc finger protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Ebfaz, Nur12, OAZ, OLF 1/EBF associated zinc finger, OLF1/EBF associated zinc finger protein, Olf1/EBF-associated zinc finger protein, Roaz, Smad and Olf interacting zinc finger protein, Smad- and Olf-interacting zinc finger protein, ZFP423, ZN423_HUMAN, ZNF423, ZNF423 zinc finger protein 423, Zfp104, Zinc finger protein 423, hOAZ, homolog of, mouse, zinc finger protein 423, Early B cell factor associated zinc finger protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ZNF423/OAZ |
| Short name: |
ZNF423/OAZ Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ZNF423/OAZ (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16762 |
| Gene: |
ZNF423 |
More about : ZNF423 |
| Long gene name: |
zinc finger protein 423 |
| Synonyms: |
KIAA0760 OAZ Roaz Ebfaz Zfp104 NPHP14 JBTS19 |
| Synonyms name: |
OLF-1/EBF associated zinc finger gene Smad- and Olf-interacting zinc finger protein early B-cell factor associated zinc finger protein |
| Locus: |
16q12, 1 |
| Discovery year: |
2004-04-06 |
| GenBank acession: |
AB018303 |
| Entrez gene record: |
23090 |
| Pubmed identfication: |
9872452 10660046 |
| RefSeq identity: |
NM_015069 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000173491 |