SPHK1 Antibody

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Catalog number: F40149-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: SPHK1 Antibody
Quantity: 0.08 ml
Other quantities: 0.08 ml 199€ 0.1mg 389€ 0.1ml 263€ 0.4 ml 406€ 1 vial 521€ 100ul 426€ 50ug 658€
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Category: Antibody
Concentration: 09% sodium azide, 4 with 0, In 1X PBS pH 7
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: SPHK1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IHC, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
Notes: Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This SPHK1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q9NYA1
Purity: Purified
Description: Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, Intracellularly, MIM 173430) and serum, Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), and extracellularly, including platelet-derived growth factor (e, it is a ligand for EDG1 (MIM 601974), it regulates proliferation and survival, the enzyme that catalyzes the phosphorylation of sphingosine, SPHK1 is a novel lipid messenger with both intracellular and extracellular functions, g
Immunogen: A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SPHK1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: SPHK1
Short name: SPHK1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: sphin this GO sine kinase 1 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: SPHK, SPHK1 and IDBG-643068 and ENSBTAG00000008507 and 618605, SPHK1 and IDBG-69650 and ENSG00000176170 and 8877, Sphk1 and IDBG-214470 and ENSMUSG00000061878 and 20698, nuclei, protein phosphatase 2A binding, this GO :0000287 and magnesium ion binding and molecular function this GO :0001568 and blood vessel development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001956 and positive regulation of neurotransmitter secretion and biological process this GO :0003677 and DNA binding and molecular function this GO :0003951 and NAD+ kinase activity and molecular function this GO :0004143 and diacylglycerol kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006457 and protein folding and biological process this GO :0006665 and sphin this GO lipid metabolic process and biological process this GO :0006670 and sphin this GO sine metabolic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007420 and brain development and biological process this GO :0007565 and female pregnancy and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008481 and sphinganine kinase activity and molecular function this GO :0009267 and cellular response to starvation and biological process this GO :0010803 and regulation of tumor necrosis factor-mediated signaling pathway and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014075 and response to amine and biological process this GO :0016310 and phosphorylation and biological process this GO :0017050 and D-erythro-sphin this GO sine kinase activity and molecular function this GO :0019371 and cyclooxygenase pathway and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030148 and sphin this GO lipid biosynthetic process and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0032026 and response to magnesium ion and biological process this GO :0032570 and response to progesterone and biological process this GO :0032651 and regulation of interleukin-1 beta production and biological process this GO :0033198 and response to ATP and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0043005 and neuron projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046521 and sphin this GO id catabolic process and biological process this GO :0046834 and lipid phosphorylation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0051084 and 'de novo' posttranslational protein folding and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051721 and protein phosphatase 2A binding and molecular function this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070555 and response to interleukin-1 and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003677 : DNA binding and also this GO :0003951 : NAD+ kinase activity and also this GO :0004143 : diacylglycerol kinase activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding and also this GO :0008481 : sphinganine kinase activity and also this GO :0017050 : D-erythro-sphin this GO sine kinase activity and also this GO :0051721 : protein phosphatase 2A binding, this GO :0003677 : DNA binding, this GO :0003951 : NAD+ kinase activity, this GO :0004143 : diacylglycerol kinase activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, this GO :0008481 : sphinganine kinase activity, this GO :0017050 : D-erythro-sphin this GO sine kinase activity, this GO :0051721 : protein phosphatase 2A binding, sphin this GO sine kinase 1
Identity: 11240
Gene: SPHK1 | More about : SPHK1
Long gene name: sphingosine kinase 1
Synonyms: SPHK
Locus: 17q25, 2
Discovery year: 1999-02-01
GenBank acession: BC030553
Entrez gene record: 8877
Pubmed identfication: 9726979
RefSeq identity: NM_182965 NM_021972
Havana BLAST/BLAT: OTTHUMG00000180177

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