MMP-8 Antibody, ALEXA FLUOR 594

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Catalog number: bs-1913R-A594
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: MMP-8 Antibody, ALEXA FLUOR 594
Quantity: 100ul
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Long name: ALEXA FLUOR 594 Conjugated, MMP-8 Polyclonal Antibody
Also known as: Anti-MMP-8 PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: MMP-8
Specificity: This is a highly specific antibody against MMP-8
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 262-312/467
Subcellular location: Secreted, Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MMP8
Gene ID Number: 4317
Swiss Prot: P22894
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, II, III, MMP13, MMP8 degrades fibrillar collagens types I, MMP8 is heavily glycosylated, MMP8 is very similar to MMP1, Most cell types do not produce MMP8, The human MMP8 gene has the chromosomal location of 11q22, The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, The zymogen is quickly activated to the 64 Kd form, Until recently, aggrecan, and the zymogen has a mass of 85 Kd, and this breaks down to a cascade of active forms, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8, it was thought that MMP8 was produced exclusively by neutrophils, serpins and alpha 2 macroglobulin, sharing 57 % amino acid identity, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen, which then denature to gelatin at body temperature, 2-22, 3, Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Synonyms: CLG1, MMP-8, MMP8, Matrix metalloproteinase-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL, HNC
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Gene target: MMP-8
Short name: MMP-8 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, MMP-8 (Antibody to)
Alternative technique: antibodies

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