TGF Beta R3 Antibody

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Catalog number: bs-1910R
Price: 263 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: TGF Beta R3 Antibody
Quantity: 0.1ml
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Long name: TGF Beta R3 Primary Polyclonal Antibody
Also known as: TGF Beta R3 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: TGF Beta R3
Specificity: This is a highly specific antibody against TGF Beta R3
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TGFBR3
Gene ID number: 7049
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII, It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form, It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems, Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2, TGF beta III receptor, TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor, TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone, TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling, TGFB2, The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins, There are 3 forms encoded by separate genes TGFB1, These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, adhesion, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration, and TGFB3, and extracellular matrix production, can function as an inhibin coreceptor with ActRII, cell cycle progression, cellular migration, including cell differentiation, nonredundant role in TGF beta signaling, or beta glycan, type III (TGF beta III receptor) has been identified, Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: BGCAN, Betaglycan, Betaglycan proteoglycan, TGF beta Receptor III, TGF beta receptor type 3, TGF beta receptor type III, TGFB R3, TGFBR 3, TGFBR3, TGFR 3, TGFR3, Transforming Growth Factor Beta Receptor III, Transforming growth factor beta receptor III betaglycan 300kDa, Beta glycan
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: TGF Beta R3
Short name: TGF Beta R3 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: TGF b R3 (Antibody to)
Alternative technique: antibodies

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